TABLE 1.

Correlation of linezolid resistance levels with percentage of mutated 23S rRNA genesa

Enterococcal strainLinezolid MIC (μg/ml)No. of mutated genes/total no. of 23S genes (%)
E. faecium LS-120/6 (0)
E. faecium LR-681/6 (17)
E. faecium LR-9161/6 (17)
E. faecium LR-1322/6 (33)
E. faecium LR-3322/6 (33)
E. faecium LR-5322/6 (33)
E. faecium LR-8323/6 (50)
E. faecium LR-7644/6 (67)
E. faecium LR-4645/6 (83)
E. faecalis LR-21284/4 (100)
  • a Detected by sequencing (or MaeI digestion) of PCR-amplified 23S rRNA genes.