TABLE 4.

Effect of dosage and mucositis on posaconazole AUC0-24 on the last study day

Comparison groupNo. of patientsPosaconazole AUC0-24 (mg · h/liter)P valuea
MeanMedianSDRange
Mucositis grades
    0137.38.03.22.2-11.90.1483
    1-2145.94.93.51.3-11.9
Dosage groups
    I74.53.72.91.8-10.00.0457*
    II136.55.83.21.3-10.5
    III78.610.13.33.9-11.9
Dosage groups/ mucositis grades
    I/055.13.73.12.2-10.00.1933
    I/1-222.82.81.41.8-3.8
    II/068.89.51.75.8-10.5
    II/1-274.54.32.91.3-10.1
    III/027.97.95.73.9-11.9
    III/1-258.910.12.84.6-11.9
  • a *, P ≤ 0.05.