TABLE 2.

Posaconazole pharmacokinetic data for study day 1 (n = 29)

Group (no. of patients)Cmax (SD) (ng/ml)Tmax (SD) (h)AUC0-12 (SD) (mg · h/liter)AUC0-24 (SD) (mg · h/liter)
MeanMedianRange
I (7)118 (74)7.6 (3.0)8.04-12.50.96 (0.52)1.96 (1.1)
II (15)186 (126.7)8.2 (5.1)8.03-241.4 (1.0)2.96 (2.0)
III (7)116.2 (58.5)4.3 (1.6)4.52-61.1 (0.5)2.95 (1.1)