TABLE 1.

Percentage of amino acid identity of β-lactamase ERP-1 and the most closely related class A β-lactamasesa

β-Lactamase% Amino acid identity
ERP-1CTX-M-8CTX-M-9CDIVKLUA-1KLUC-1SHV-1OXY-1HUGACUMASFO-1RAHN-1YENT
ERP-1-505049494839484545464950
CTX-M8-8471837637736161727254
CTX-M9-69807937715959726955
CDIV-676834706564686453
KLUA-1-7736746363757457
KLUC-1-35726262747156
SHV-1-353434353434
OXY-1-6464736955
HUGA-94666251
CUMA-656151
SFO-1-7554
RAHN-1-54
YENT-
  • a ERP-1, E. persicina (this study); CDIV, C. koseri (formerly C. diversus) (26); KLUA-1, K. ascorbata (GenBank accession no. 272038); KLUC-1, K. cryocrescens (8); Klebsiella pneumoniae (SHV-1 [3]; OXY-1, Klebsiella oxytoca (2); HUGA, P. penneri (17); CUMA, P. vulgaris (25); SFO-1, S. fonticola (24); RAHN-1, R. aquatilis (4); YENT, Y. enterocolitica (30). CTX-M-8 and CTX-M-9 are plasmid-encoded class A enzymes (5, 28). -, 100% identity.