TABLE 4.

Responses of growth of strain mc2155 and MSH-deficient mutants to redox-cycling agents

Agent (concn [μmol])Zone of inhibition (radius [mm])
Wild typeI64Tn1Tn2
Plumbagin (0.01)13.5 ± 0.513.3 ± 1.923.0 ± 1.223.0 ± 1.0
Plumbagin (0.005)11.0 ± 1.09.3 ± 0.917.0 ± 0.615.0 ± 0.0
Menadione (0.5)19.7 ± 0.926.7 ± 0.931.3 ± 1.316.4 ± 1.9
Menadione (0.1)9.7 ± 0.38.7 ± 0.720.7 ± 3.815.3 ± 2.0
Nitrofurantoin (1.0)6.0 ± 0.68.7 ± 0.314.0 ± 2.735.0 ± 3.6
Nitrofurantoin (0.5)4.7 ± 0.35.0 ± 0.610.7 ± 2.6NDa
  • a ND, not determined.