TABLE 1.

MICs of β-lactams for K. pneumoniae Lor-1, E. coli DH10B(pLP-1), E. coli DH10B(pLP-2), and E. coli DH10B (reference strain)

β-Lactam(s)aMIC (μg/ml) for:
K. pneumoniae Lor-1 (SHV-38)E. coli DH10B (pLP-1) (SHV-38)E. coli DH10B (pLP-2) (SHV-1)E. coli DH10B
SHV-38SHV-1
Amoxicillin>512>512>5124
Amoxicillin + CLA>512>512644
Ticarcillin>512>512>5124
Ticarcillin + CLA>512>5121284
Piperacillin>512>512>5122
Piperacillin + TZB>512>5122562
Cephalothin128512324
Cefuroxime41684
Cefoxitin4888
Ceftazidime166420.25
Ceftazidime + CLA2810.25
Cefotaxime0.250.50.120.06
Ceftriaxone0.120.250.060.06
Cefepime240.250.03
Cefpirome240.50.03
Cefpirome + CLA0.120.50.060.03
Aztreonam240.250.12
Moxalactam120.250.06
Moxalactam + CLA0.250.50.120.12
Imipenem0.250.50.060.06
Meropenem0.060.120.060.06
  • a CLA, clavulanic acid at a fixed concentration of 2 μg/ml; TZB, tazobactam at a fixed concentration of 4 μg/ml.