TABLE 3.

ELISA determination of β-lactamase production of Gly238 mutants

aa variationaSHV production (ng/ml)b
Gly (wt)370
Ala151
Ser90
Cys7
Pro6
Asp101
Thr13
Asn45
Val9
Glu12
Gln15
His91
Ile10
Leu6
Met9
Lys14
Phe56
Tyr12
Arg14
Trp9
SK−0.03
  • a aa, amino acid; wt, wild type.

  • b ±6% error (8).