TABLE 4.

Resistance profiles of EC251 and EC3006 and their respective transconjugants and clonesa

AntibioticMIC (μg/ml)
HB101DH5αEC251HB101 251TCDH5α (pBG251)EC3006HB101 3006TCDH5α(pBG3006)
AMX4≤2>64>64>64>64>64>64
AMX-CLAV4≤2321632321632
TIC≤4≤4>128>128>128>128>128>128
PIP≤4≤4>12864>128>128>128>128
PIP-TZ≤4≤412816>128>128128>128
CZ2116432>25632256
CZ-CLAV11411211
CXM423286432816
CXM-CLAV2116441642
FOX4232421642
CPD10.54116412
CPD-CLAV0.50.520.50.520.50.25
CAZ0.50.250.50.250.2510.50.5
CAZ-CLAV0.250.250.250.250.120.50.250.25
CTX0.120.0610.540.50.120.12
CTX-CLAV0.120.060.250.120.120.50.060.06
ATM0.250.060.50.120.50.50.250.12
ATM-CLAV0.120.060.50.120.060.250.120.12
FEP0.060.0621>320.50.120.5
FEP-CLAV0.060.030.120.120.250.120.060.12
  • a EC251 and its corresponding transconjugant (HB101 251TC) and clone [DH5α (pBG251)] harbored an OXA-30 β-lactamase (see characterization of phenotype C) and EC3006 and its corresponding transconjugant (HB101 3006TC) and clone [DH5α (pBG3006)] harbored a TEM-1 β-lactamase.