TABLE 4.

Complementation of OpmG and OpmH mutants with OpmG and OpmH

StrainPhenotype of strain and plasmidMIC (μg/ml)a
KmGmSmEryClinFusCmTcCbImiMerCtzNalNfxPmbAcrCV
H911PAK wild type1000.88125>750161251.3501.60.630.08310.250.1632125
H958OpmG130.11633754125>20501.60.630.08310.250.1632125
H958 (pJJ107)OpmG + OpmG250.88250>75016125>208001.60.630.08310.250.0832125
H966OpmH130.42633752125>20500.80.150.08310.250.16416
H743 (pJJ109)OpmH + OpmH250.84125>7508250>208001.60.150.08310.250.31663
  • a Abbreviations: Km, kanamycin; Gm, gentamicin; Sm, streptomycin; Ery, erythromycin; Clin, clindamycin; Fus, fusidic acid; Cm, chloramphenicol; Tc, tetracycline; Cb, carbenicillin; Imi, imipenem; Mer, meropenem; Ctz, ceftazidime; Nal, nalidixic acid; Nfx, norfloxacin; Pmb, polymyxin B; Acr, acriflavin; CV, crystal violet.