TABLE 2.

MICs

aaaaa side chain vol (Å3)bMIC (μg/ml)
AmpicillinPiperacillinCephaloridineCephalothinCefotaximeCeftazidimeAztreonamCefepime
G16,0002,000128320.06110.5
A28.58,2002,0002565128842
S28.98,2001,00016648810.5
C48.44,10051216642842
P52.6328440.060.030.50.06
D51.012864440.12540.50.125
T56.08,2001,0001616480.50.25
N54.04,100512321284821
V79.92,000256440.540.50.06
E78.3512128440.540.50.06
Q83.751212844280.50.25
H93.11,00025616320.5411
I106.62,00051284240.50.25
M102.82,000256816280.50.125
L106.651225616320.580.51
K108.52,000256816180.50.125
F129.851225632320.2540.51
Y133.5256128880.12580.1250.06
R113.351212816641820.5
W167.7128128440.2580.1250.25
  • a aa, amino acid.

  • b Gly is taken as the reference amino acid. All volumes listed are relative to the side chain of Gly.