Variable | Test treatment | Reference treatment | Point estimate (%) | 90% confidence interval limit | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|

Lower limit | Upper limit | |||||||||||

ABT-773 | M-1 | ABT-773 | M-1 | ABT-773 | M-1 | |||||||

C_{max}^{b} | B | A | 74.3 | 72.6 | 61.0 | 59.3 | 90.5^{d} | 88.9 | ||||

C | A | 97.1 | 101.2 | 79.7 | 82.6 | 118.4 | 123.9 | |||||

AUC_{0-last}^{b} | B | A | 82.8 | 76.7 | 68.3 | 61.8 | 100.4 | 95.3 | ||||

C | A | 101.8 | 101.1 | 84.0 | 81.4 | 123.5 | 125.6 | |||||

AUC_{0-∞}^{b} | B | A | 84.2 | 78.3 | 69.8 | 63.9 | 101.7 | 95.9 | ||||

C | A | 102.0 | 100.9 | 84.5 | 82.3 | 123.2 | 123.5 | |||||

t_{1/2}^{b} | B | A | 109.8 | 95.3 | 100.4 | 83.4 | 120.0 | 108.9 | ||||

C | A | 101.7 | 106.2 | 93.0 | 92.9 | 111.2 | 121.3 | |||||

T_{max}^{c} | B | A | 114.0 | 104.7 | 92.4 | 84.9 | 135.5 | 124.4 | ||||

C | A | 107.0 | 107.0 | 85.4 | 87.2 | 128.5 | 126.7 | |||||

MRT^{c} | B | A | 111.6 | 98.1 | 104.7 | 88.9 | 118.4 | 107.3 | ||||

C | A | 101.7 | 101.6 | 94.8 | 92.3 | 108.5 | 110.8 |