TABLE 1.

Compilation of previously reported and verified MICs and described resistance mechanisms for C. albicans isolates used in this study

IsolateAlternate isolate nameaMIC (μg/ml)aPreviously described resistance mechanism(s)a
Previously determinedaThis study
2-79220.25
2-80384Increased expression of MDR1
8-46153216Increased expression of MDR1 and ERG11, loss of allelic variation in ERG11, point mutation in ERG11
12-9917>64>64Increased expression of MDR1 and ERG11, loss of allelic variation in ERG11, point mutation in ERG11, increased expression of CDR1 and CDR2
  • a As reported in reference 55.