TABLE 3.

Antifungal susceptibilities of S. cerevisiae clones expressing ckCYP51, caCYP51, or the backbone vector

Gene or vector expressedMIC (μg/ml)
S. cerevisiae AH22S. cerevisiae TY310
FluconazoleVoriconazoleFluconazoleVoriconazole
ckCYP512560.25320.03
caCYP51320.0620.008
pESC-LEU160.030.5<0.004