TABLE 2.

Concentrations of fluconazole and voriconazole required to inhibit the growth and CYP51s of C. krusei and C. albicans

OrganismMIC (μg/ml)Mean IC50 (μg/ml) ± SD
FluconazoleaVoriconazoleFluconazoleaVoriconazole
C. krusei 91-1161320.50.243 ± 0.1300.014 ± 0.004
C. krusei 91-1159320.50.152 ± 0.0640.020 ± 0.005
C. krusei 91-1158640.50.230 ± 0.1180.020 ± 0.005
C. albicans SC531410.0310.010 ± 0.0020.0020 ± 0.0006
  • a Results are from our previous work (17).