TABLE 3.

A single dose of 0.5% lysostaphin cream (∼150 μg of lysostaphin) eradicates S. aureus nasal colonization of cotton rats by all strains of S. aureus tested

S. aureus strainControl groupLysostaphin-treated group
No. of rats colonized/no. testedMean colonization (CFU)No. of rats colonized/no. testedMean colonization (CFU)
ATCC 49521 (type 5)5/5>10,0000/50
ATCC 12605 (type 8)5/55,4180/50
MRSA 12/125/55670/50
SA 3865 MupR5/52680/50