TABLE 1.

MICs determined before and after exposure of S. aureus to two fluoroquinolones

FluoroquinoloneDuration of treatment (days)MIC (μg/ml)
Before treatmentJust after samplingAfter 3rd passageAfter 7th passageAfter 10th passage
Moxifloxacin30.090.250.250.190.19
40.370.310.310.37
50.50.50.50.5
Levofloxacin30.6110.750.75
4221.51.5
5221.51.5