TABLE 3

CFU of S. anginosus LMG 14502 killed per biofilm after treatment with ciprofloxacin, levofloxacin, or tobramycin when grown in biofilm medium or in diluted biofilm supernatant of S. aureus LMG 10147 or W8a

Antibiotic solution (concn [μg/ml])Log CFU (avg ± SD) killed of a monospecies S. anginosus LMG 14502 biofilm, grown and treated in:
Biofilm mediumSN of S. aureus LMG 10147SN of S. aureus W8
Ciprofloxacin (150)3.73 ± 0.972.12 ± 0.753.52 ± 0.52
Levofloxacin (500)3.83 ± 0.393.05 ± 0.622.83 ± 0.29
Tobramycin (200)4.77 ± 1.314.43 ± 0.984.42 ± 0.25
  • a n ≥ 3. No significant differences could be observed (P > 0.05). SN, supernatant.