TABLE 3.

Inhibition of select LasR-controlled genes in P. aeruginosa MW1a

Gene numberGene nameFold induction in:% Inhibition by:
V-06-018PD12
MW1PAO1MW1PAO1MW1PAO1
PA1001phnA7339985585
PA1002phnB17893397−13
PA1431rsaL33365928334624
PA18945316519442
PA18978130−25242120
PA230282010322714
PA2303347930343816
PA25876738254722
PA2592510563138−14
PA3477rhlR4852419−12
PA3724lasB9129468587429
PA390791857262629
  • a The concentration of 3OC12-HSL in the growth medium for P. aeruginosa MW1 was 0.3 μM. A negative value indicates percent activation.