TABLE 2

Extrapolated %f TMICa achieved with a human exposure of 2 g cefiderocol every 8 h as a 1- or 3-h infusion in infected rats

Cefiderocol MIC (μg/ml)%f TMIC with an infusion time of:
1 h3 h
0.125100100
0.25100100
0.5100100
1100100
2100100
475100
850100
  • a %fTMIC, percentage of the dosing interval during which free drug concentrations are above the MIC.