TABLE 2.

Resistance profiles of donor strains and transconjugants

Group and strainMIC (μg/ml)
CIPaAMPCTXGENSXTSMZTMPCHLTET
Clinical strains (donors)
    464≥512≥512≥512≥512≥512≥128≥512≥512
    7128≥512≥512≥512≥512≥512≥128≥512128
    10128≥512≥512≥512≥512≥512≥12864256
    12128≥512≥512≤1≥512≥512≥12864256
    2964≥512256≤1≥512≥512≥12864256
    76≥256≥51264≥512≥512≥512≥128256256
Recipient, J53Az0.008160.030.1250.5160.12541
Transconjugantsb
    4-30.25≥512328≥512≥512≥12851232
    4-590.25≥51220.125≥512≥512≥128≥51264
    7-24.10.125≥51282≥512≥512≥1282561
    7-24.20.12532≤0.0310.5≥5120.12541
    10-50.2532≤0.030.125≥512≥512≥128464
    10-21≥5120.060.1251≥5120.125464
    12-41≥5120.060.1251≥5120.125464
    29-111≥5120.060.1250.5≥5120.125464
    76-652≥5128128≥512≥512≥128256128
  • a CIP, ciprofloxacin; AMP, ampicillin; CHL, chloramphenicol; CTX, cefotaxime; GEN, gentamicin; SMZ, sulfamethoxazole; TET, tetracycline; TMP, trimethoprim.

  • b qnr is located on different-size plasmids for transconjugants 4-3 and 4-59, as well as 7-24.1 and 7-24.2, whereas qnr is located on the same-size plasmids for 10-5 and 10-2. For another transconjugant, 12-5, the MICs were the same as those for 12-4.