TABLE 1.

Checkerboard assay of FLC and Mycograb versus yeast isolates examined

SpeciesAgentMIC (μg/ml) of each agentFIC (μg/ml)FICIOutcome
AloneIn combination
C. albicans (FLC-S)FLC1.560.40.260.34Synergy
Mycograb128100.08
C. albicans (FLC-R)FLC5012.50.250.64Indifference
Mycograb2561000.39
C. kruseiFLC100500.51.28Indifference
Mycograb1281000.78
C. tropicalisFLC3.123.121.01.78Indifference
Mycograb1281000.78
C. glabrataFLC6.251.560.250.75Indifference
Mycograb128640.5
C. parapsilosis (NCPF3104)FLC1.561.5611.39Indifference
Mycograb2561000.39
C. parapsilosis (clinical isolate)FLC1.561.5611.39Indifference
Mycograb2561000.39