TABLE 2.

Checkerboard assay of AMB and Mycograb versus yeast isolates examined

SpeciesAgentMIC (μg/ml) of each agentFIC (μg/ml)FICIOutcome
AloneIn combination
C. albicans (FLC-S)AMB10.030.030.09Synergy
Mycograb12880.06
C. albicans (FLC-R)AMB0.50.1250.250.27Synergy
Mycograb25640.02
C. kruseiAMB10.250.250.28Synergy
Mycograb12840.03
C. tropicalisAMB0.1250.0160.130.16Synergy
Mycograb12840.03
C. glabrataAMB10.250.250.31Synergy
Mycograb12880.062
C. parapsilosis (NCPF3104)AMB10.250.250.27Synergy
Mycograb25640.016
C. parapsilosis (clinical isolate)AMB10.250.250.27Synergy
Mycograb25640.016