TABLE 1

MIC of antimicrobial agents to M. abscessus strains

StrainMIC50 (μg/ml)
LCB01-0371BedaquilineLinezolidSutezolidAmikacinClarithromycinCefoxitin
M. abscessus ATCC 199771.20.52.11.87.40.114.0
M. abscessus clinical isolates
    KMRC 00136-610382.5
    KMRC 00136-610390.7
    KMRC 00136-6104022.3
    KMRC 00136-610412.9
    KMRC 00200-611983.5
    KMRC 00200-611991.7
    KMRC 00200-612001.2
    KMRC 00200-612011.6
Drug-resistant mutant
    LCB01-0371R28.50.518.429.40.1
    AMK-R1.3>50
    CFX-R1.6>40
    CLA-R1.5>70