TABLE 4.

Activities of quinolones against hyperpermeable E. coli strains

StrainRelevant genotypeMIC (μg/ml)
PGE-8367769Nalidixic acidCiprofloxacin
D21Wild type240.008
D22lpxC1010.510.004
DM200tolC6::mini-Tn100.250.50.004
DM202lpxC101 tolC6::mini-Tn100.1250.25≤0.001