TABLE 3

Cox regression analyses of prognostic factors associated with 30-day mortality among patients with breakthrough Acinetobacter bacteremia during carbapenem therapy

VariableUnivariate analysisMultivariate analysis
HR (95% CI)aPHR (95% CI)aP
APACHE II scoreb1.044 (1.015–1.074)0.0031.049 (1.020–1.080)0.001
Recent surgery0.508 (0.262–0.983)0.044
Catheter-related infection1.842 (1.003–3.384)0.0491.984 (1.075–3.660)0.028
Bacteremia due to A. baumannii1.866 (1.086–3.205)0.024
Bacteremia due to A. pittii0.422 (0.153–1.167)0.097
Tigecycline-based therapy2.142 (1.124–4.082)0.0213.659 (1.794–7.465)<0.001
Appropriate therapy0.637 (0.373–1.088)0.099
  • a HR, hazard ratio; CI, confidence interval.

  • b APACHE II, Acute Physiology and Chronic Health Evaluation II.