TABLE 5.

Effect of complementation with wild-type AcrR on fluoroquinolone susceptibility

StrainaMIC (μg/ml)b
NorfloxacinCiprofloxacin
S5>25664
S5/pTS003acrR968
S5/pTS00312864
S10>25664
S10/pTS003acrR648
S10/pTS00312864
S13>256>128
S13/pTS003acrR25664
S13/pTS003>256>128
S36>256>128
S36/pTS003acrR19264
S36/pTS003>256>128
S7968
S7/pTS003acrR642
S7/pTS003648
  • a pTS003acrR is the vector containing Klebsiella acrR; pTS003 contains the vector only.

  • b MIC were determined by E-test (norfloxacin) and doubling agar dilutions (ciprofloxacin).