TABLE 1.

Correlation of linezolid MICs to the number of G2576T mutated 23S rRNA genes in E. faecalis JH2-2 mutants

Linezolid MIC (μg/ml)No. of amplification products digested with MaeI/no. of colonies screened (%)No. of G2576T mutated genes/total no. of 23S rRNA genes (%)
45/10 (50)2/4 (50)
84/12 (33)2/4 (50)
168/12 (67)3/4 (75)
329/11 (81)3/4 (75)
6410/12 (83)3/4 (75)
12817/17 (100)4/4 (100)