TABLE 2.

Susceptibilities of C. albicans and S. cerevisiae wild-type and mutant strains to SBI and non-SBI antifungals

AntifungalTime (h)MIC
C. albicansS. cerevisiae
Ca-CAF2-1Ca-cdc35Ca-cap1Sc-BY4743Sc-srv2Sc-W303-1ASc-cyr1-2
Fluconazole241UGa0.258UG8UG
48>80.50.5>82>81
72>80.50.5>82>84
Itraconazole240.12UG<0.064UG2UG
48>4<0.06<0.06>40.5>40.25
72>4<0.06<0.06>41>41
Miconazole240.008UG<0.0040.31UG0.008UG
48>0.25<0.004<0.0040.06<0.0040.06<0.004
72>0.250.008<0.0040.12<0.0080.060.008
Terbinafine240.5UG<0.252UG0.5UG
4880.251>160.2542
7280.52>160.5164
Fenpropimorph240.25UG0.060.5UG0.12UG
480.50.250.25>0.50.030.50.25
72>0.50.50.25>0.50.060.50.5
Amphotericin B240.12UG0.120.12UG0.125UG
480.250.060.50.5<0.060.250.25
720.250.250.50.50.060.50.5
Caspofungin240.06UGNDb0.12UG0.25UG
480.120.06ND0.250.25>0.250.25
720.250.12ND0.250.25>0.25>0.25
  • a UG, undetectable growth.

  • b ND, not done.