TABLE 1.

In vitro activities of TD-6424 and comparator antibiotics against MRSA and MSSA

OrganismNo. of strainsAntimicrobial agentMIC (μg/ml)
Range50%90%
MRSA128TD-6424≤0.06-211
128Vancomycin0.5-212
39Teicoplanin0.5-1614
128Linezolid0.5-424
128Oxacillin4->6464>64
MSSA47TD-64240.12-20.51
47Vancomycin0.5-222
38Teicoplanin0.5-212
47Linezolid2-422
47Oxacillin0.13-20.51