TABLE 1.

MIC90sa of antimicrobial agents for the studied multiresistant isolates

Type of isolate (n= 100)No. of blaCTX-M-2- negative isolatesNo. of blaCTX-M-2- positive isolatesMIC90 (μg/ml)
AMPbCTXCAZAMKGENIPM
Acinetobacter spp.201>1,024 (512->1,024)256 (16-512)32 (8-512)16 (0.5-64)512 (2->512)1 (0.5-2)
Citrobacter freundii 40>1,02464(512->1,024)(4-32)(2-128)(0.25-2)
Enterobacter cloacae 41>1,024256 (32-512)512 (1-512)4 (0.5-4)512 (8->512)0.5 (0.12-2)
Escherichia coli 22>1,02416(8-16)16640.06
Klebsiella pneumoniae 1010>1,024>512 (128->1024)512 (4-512)16 (4-16)64 (32-512)0.12 (<0.12-0.5)
Proteus mirabilis 212>1,024>128 (8->512)1 (0.5-16)32 (8-64)128 (64-512)0.5 (0.5-2)
Pseudomonas aeruginosa 104NDND32 (4-128)4 (4-64)128 (2->512)1 (0.5-2)
Salmonella spp.22>1,024(16-128)(2-64)(64-128)(32-128)(0.06-0.5)
Serratia marcescens 73>1,02416 (4-128)2 (0.5-32)32 (0.5-128)64 (16-256)0.5 (0.25-0.5)
Stenotrophomonas maltophilia 40NDND(1-128)(64-256)(32-64)(64-128)
  • a MIC90 is the MIC at which 90% of the isolates tested are inhibited. Minimum and maximum MICs are shown in parentheses.

  • b AMP, ampicillin; CTX, cefotaxime; CAZ, ceftazidime; AMK, amikacin; GEN, gentamicin; IPM, imipenem; ND, not determined.