TABLE 2.

Antiviral activity of dendrimers against HSV-2 determined by plaque reduction assaya

DendrimerEC50 (μg/ml)CC50 (μg/ml)b
SPL70130.6c>1,000
SPL70150.5>1,000
SPL70320.7>1,000
  • a Evaluations were repeated five times for SPL7013, twice for SPL7015, and once for SPL7032.

  • b CC50, cytotoxic concentration.

  • c The standard deviation was 0.03 μg/ml.