TABLE 1.

Overall susceptibilities of the vancomycin-resistant Enterococcus species strain collection to daptomycin and the comparative agents by the NCCLS broth microdilution method using calcium-supplemented Mueller-Hinton broth test medium

DrugMIC (μg/ml)% Resistanta
50%90%Range
Van A and Van B strains
    Daptomycin480.5-8NA
    Linezolid221-321.5
    Quinupristin-dalfopristin0.510.25-166.0
    Ampicillin64128≤0.5->12893.2
    Doxycycline416≤0.25-3214.2
    Vancomycin>128>12832->128100
VanC1 and VanC2 strains
    Daptomycin120.5-8NA
    Linezolid222-40
    Quinupristin-dalfopristin221-20
    Ampicillin0.510.5-20
    Doxycycline≤0.25≤0.25≤0.25-164.5
    Vancomycin444-80
  • a MIC interpretive criteria from NCCLS M100-S13 (20). NA, not applicable.