TABLE 3.

Evaluation of three expanded-spectrum dendrimer products against genital herpes in miceb

TreatmentConcn (mg/ml)Fraction (%) of animals protected against:
DiseaseInfection
SPL701310011/11 (100)a11/11 (100)a
SPL70151009/12 (75)a8/12 (67)a
SPL703210011/12 (92)a11/12 (92)a
PBS0/12 (0)0/12(0)
  • a P < 0.005 versus PBS.

  • b Mice were treated 20 s prior to challenge.