TABLE 3.

Susceptibility test and genotype of artemether resistance isolate at day 0 and day 21a

DayIC50 (nM) forGenotyping result
ArtemetherChloroquineQuinineHalofantrineLumefantrineMefloquineDoxycyclineMicrosatellite (bp)% of isolates carrying PfATPase6
DHFRPFE14FC3M35C4M79Wild typeS769N mutant
012767321.320.92.45,800961322072105446
194
218.275282.1353.27,50096132207194100
  • a Values for in vitro susceptibility tests and genotypes are shown for the artemether resistance strain ex vivo isolates collected in 2,005 and results with the same isolates after 21 days of continuous cultivation.