TABLE 1.

Antimalarial regimens recommended for French Guiana by the 1990, 1995, and 2002 consensus meetings

Yr of consensus meetingClinical formTherapyProphylaxis
First-lineSecond-line
1990MildChloroquinebHalofantrinec or mefloquinedMefloquinee
SevereQuinineaChloroquine-proguanilf
1995MildQuinine-doxycyclinehHalofantrinei or mefloquineMefloquinee or doxycyclinej
SevereQuinine-doxycyclineg
2002MildArtemether-lumefantrinekAtovaquone-proguanillAtovaquone-proguanilm
SevereQuinine-doxycyclinegDoxycyclinej
  • a Total dose of 24 to 30 mg quinine base/kg of body weight.

  • b Forty milligrams per day for 4 days.

  • c Five hundred milligrams, 3 times per day.

  • d 1.5 g, 3 times per day.

  • e Two hundred fifty milligrams per week until 4 weeks after the patient's return, if <1-month stay.

  • f Chloroquine, 5 mg/kg per week, plus proguanil, 3 mg/kg per day, until 6 weeks after the patient's return, if 1- to 3-month stay.

  • g Quinine, 20 mg/kg intravenously for 4 h, and then 10 mg/kg/8 h, plus doxycycline, 3 mg/kg.

  • h Quinine, 25 mg/kg for 5 days, plus doxycycline, 3 mg/kg for 5 days.

  • i 24 mg/kg, 3 times per day.

  • j 100 mg per day for adults, until 4 weeks after the patient's return.

  • k Artemether, 20 mg, plus lumefantrine, 120 mg, 4 tablets of each 6 times per day.

  • l Atovaquone, 250 mg, plus proguanil chlorhydrate, 100 mg, 4 tablets of each per day for 3 days.

  • m 1 tablet per day until 7 days after the patient's return.