TABLE 1.

Kinetic analysis for ETV-TP

EnzymedGTP Km (μM)ETV-TP IC50 (μM)ETV-TP Ki (μM)Ki/Km
Pol γ0.12>300b>160b>1333
HBV-RTa0.00130.000430.00020.15
  • a Data reproduced from Levine et al. (26).

  • b No incorporation was seen at 300 μM ETV-TP.