TABLE 5.

Meropenem target attainment against P. aeruginosa using four different dosing regimens

MIC% of isolates inhibited by:
1 g q8h (3 h)a1 g q8h (1 h)500 mg q8h (3 h)500 mg q8h (1 h)500 mg q6h (1 h)
0.00810010010099.95100
0.01610010010099.8100
0.12510099.9910099.45100
0.2510099.9710098.6599.84
0.510099.8210095.499.36
1.010099.2810089.6597.04
2.010096.2199.2565.4588.04
4.099.181.0879.631.963.02
8.079.623.1214.24.419.08
16.014.20000
32.000000
Target attainment86.479.579.367.576.4
  • a Values in parentheses are infusion times.