TABLE 2.

MAb treatment of mice infected with SM and MC switch variants

Infection and treatment regimenMedian days of survivala
SM controlSM + MAbMC controlMC + MAbP valueb
104 cells i.t. + 1 mg of MAb9912932480.0018
105 cells i.t. + 1 mg of MAb53532932No difference
106 cells i.t. + 1 mg of MAb597631380.03
5 × 106 cells i.p. + 0.5 mg of MAb310430.02
105 cells i.p. + 0.5 mg of MAb394545No difference
  • a n = 10 mice per treatment group.

  • b Log rank denotes difference in survival.