TABLE 2.

Effects of target modification on BM0 activity against S. cerevisiae

StrainMIC (μM) at pH 7.0
T48 (wild type)0.91
ΔN0.91
ΔC0.91
ΔNΔC0.91
ATCC1026115
CTM1+20.46
CTM3+40.91
CTM1+2+3+40.91
AD/PDR5+1.82
AD/PDR5−1.82