TABLE 3

The Gly45Cys mutant of NuoB provides resistance against the antibacterial activity of D73

StrainGenotypeMIC (μM)Relative MICa
BJM1072Schu S4(pFNLTP-6-groEL)0.24
BJM1225Schu S4(pAQ367)(pFNLTP-6-groEL-nuoB+)0.24
BJM1224Schu S4(pAQ568)(pFNLTP-6-groEL-nuoB-G45C)1.88
BJM1221ΔguaB mutant(pFNLTP-6-groEL)0.23
BJM1217ΔguaB mutant(pAQ367)(pFNLTP-6-groEL-nuoB+)0.94
BJM1219ΔguaB mutant(pAQ568)(pFNLTP-6-groEL-nuoB-G45C)3.7516×
BJM1220AQ3(pFNLTP-6-groEL)1.88
BJM1216AQ3(pAQ367)(pFNLTP-6-groEL-nuoB+)3.75
BJM1218AQ3(pAQ568)(pFNLTP-6-groEL-nuoB-G45C)3.75
  • a The relative MIC is the ratio of the MIC to that of the appropriate vector control.