TABLE 3.

Effect of the putative EPI NMP and of PAβN on MICs of different drugs in efflux pump-overexpressing E. coli strains 2-DC14PS and 3-AG100MKX and ΔacrAB control strain 1-DC14PS

StrainDrugMIC (μg/ml) with:
No EPINMP (100 μg/ml)PAβN (25 μg/ml)
1-DC14PSLevofloxacin0.1250.1250.06
Linezolid16168
Clarithromycin221
Oxacillin≤0.5≤0.5≤0.5
Rifampin82≤0.06
Chloramphenicol111
Tetracycline10.50.25
2-DC14PSLevofloxacin40.251
Linezolid5121664
Clarithromycin256328
Oxacillin641632
Rifampin1640.25
Chloramphenicol811
Tetracycline20.52
3-AG100MKXLevofloxacin40.50.5
Linezolid2561664
Clarithromycin256322
Oxacillin641632
Rifampin1640.125
Chloramphenicol812
Tetracycline20.52