TABLE 2.

Reasons for inappropriate initial antimicrobial therapy

Reasons for inappropriate therapyNo. of patients
E. coli (n = 31)K. pneumoniae (n = 23)Enterobacter (n = 37)P. aeruginosa (n = 60)
Cephalosporin use and resistance to druga111221
Combination therapy and resistance to multiple drugs1710115
Monotherapy and resistance to drugb31117
Monotherapy with aminoglycoside in Pseudomonasc33
No therapy0045
  • a Applied to bloodstream infections caused by E. coli, K. pneumoniae, and Enterobacter spp.

  • b Patients who received cephalosporin monotherapy for bloodstream infections caused by E. coli, K. pneumoniae, or Enterobacter spp. were not included. Those were classified under cephalosporin use and resistance to drug.

  • c Applied to P. aeruginosa bacteremia.