TABLE 1.

Characteristics of the S. enterica serovar Schwarzengrund strains studied

SerovarStrainOriginaYear of isolationAntibiotic resistance profilebMICs quinolones (μg/ml)bSubstitutions in QRDRc
NALFLUENRMARCIPGyrAParCParE
SchwarzengrundCGST2T2000Ap Cm Sm Sp Su Tc Tm>1,024 [512]>1,024 [64]256 [4]32 [4]64 [16]Ser83Phe; Asp87GlyThr57Ser, Ser80ArgSer458Pro
SchwarzengrundCGST3T2000Ap Cm Sm Sp Su Tc Tm>1,024 [512]1,024 [64]64 [4]16 [4]16 [8]Ser83Phe; Asp87AsnThr57Ser; Glu84Lys
SchwarzengrundCGST4T2001Ap Cm Sm Sp Su Tc Tm>1,024 [512]>1,024 [64]256 [4]32 [4]64 [16]Ser83Phe; Asp87GlyThr57Ser; Ser80ArgSer458Pro
SchwarzengrundCGST5T2002>1,024 [512]>1,024 [128]64 [4]16 [2]16 [4]Ser83Phe; Asp87GlyThr57Ser; Ser80Arg
Controls Schwarzengrund383SA99B1999410.0600.0300.030Thr57Ser
    Hadar13SA02B2002410.1250.0600.030Thr57Ser
    TyphimuriumS/921495S199240.50.1250.0600.030
  • a T, Taiwan; B, Belgium; S, Scotland.

  • b Antibiotics are ampicillin (Ap), chloramphenicol (Cm), streptomycin (Sm), spectinomycin (Sp), sulfonamide (Su), tetracycline (Tc), trimethoprim (Tm), nalidixic acid (NAL), flumequine (FLU), enrofloxacin (ENR), marbofloxacin (MAR), and ciprofloxacin (CIP). Numbers in brackets are the MICs in the presence of PABN at 80 μg/ml.

  • c No GyrB substitutions were detected.