TABLE 2.

Antibiotic susceptibility distributions of 14 antimicrobials against 197 isolates of H. influenzaea

AntibioticMIC (μg/ml)PbGeometric mean
MIC50MIC90Range
19972007199720071997200719972007% Variation
Amoxicillin10.5≥6432≤0.25-≥64≤0.25-≥640.052.831.67-41.0
Amoxicillin-clavulanic acid0.50.5220.25-40.25-40.490.780.84+7.69
Cefaclor4416161-32≤0.5-320.0035.234.43-15.30
Cefuroxime11440.25-80.25-80.071.161.07-7.76
Cefotaxime≤0.01≤0.010.060.06≤0.01-0.12≤0.01-0.250.940.180.180.00
Cefixime≤0.06≤0.06≤0.06≤0.06≤0.06-0.5≤0.06-0.250.660.0630.062-1.59
Cefpodoxime≤0.06≤0.060.250.25≤0.06-0.25≤0.06-0.50.850.0840.086+2.38
Chloramphenicol≤0.5≤0.51≤0.5≤0.5-8≤0.5-80.0080.630.54-14.29
Tetracycline≤0.5≤0.5≤0.5≤0.5≤0.5-≥8≤0.5-40.140.550.51-7.27
Telithromycin≥2≥2≥2≥20.5-≥20.5-≥20.191.721.73+0.58
Clarithromycin8816162-322-160.659.158.91-2.62
Azithromycin22440.25-80.5-80.00011.602.19+36.88
Trimethoprim-Sulfamethoxazole1≤0.251616≤0.25-≥64≤0.25-320.031.690.97-42.60
Ciprofloxacin≤0.03≤0.03≤0.03≤0.03
  • a Significant values are indicated in boldface.

  • b As determined by an unpaired t test.