TABLE 2.

Susceptibility of P. aeruginosa ATCC 15442 biofilms to single-agent treatments, as determined by high-throughput screening (using CBDs)a

Metal ion or biocide (concn unit)MBCb
5 min (in ddH2O)30 min (in ddH2O)24 h (in 10% TSB-ddH2O)
Ag+ (mM)>19>19>19
Cu2+ (mM)>32>3232 (16 to 32)
Al3+ (mM)>76>76 (38 to >76)76 (76 to >76)
SeO32− (mM)>16>16>16
Zn2+ (mM)>31>31>31
Polycide (ppm)>3,200 (50 to >3,200)1,800 (100 to >3,200)400 (50 to 800)
Stabrom (ppm)250 (31 to >500)250 (16 to >500)94 (63 to >1,600)
Isopropyl alcohol (%)0.50 (0.25 to 0.50)0.50 (0.25 to 0.50)0.50 (0.25 to >0.50)
Virox (ppm)313 (156 to 5,000)313 (156 to 2,500)625 (313 to 2,500)
  • a Note that these assays were performed using a high-throughput screening method that judges killing qualitatively. Incomplete killing of microbial populations may still occur with short exposure times, but this is not detected by the high-throughput method employed here.