TABLE 1.

Anti-influenza virus activities and cytotoxicities of T-705 and ribavirina

CompoundIC50 (μM)bCC50 (μM)c
T-7051.0 ± 0.9>6,370
Ribavirin31.6 ± 9.294.3 ± 47.6
  • a The values are means ± standard deviations for three independent experiments.

  • b Activity against influenza A PR/8/34 virus.

  • c Cytotoxicity in MDCK cells.