TABLE 4.

Appropriateness of initial antimicrobial treatment by antibiotica

Drug classNo. (%) appropriate (n = 230)No. (%) inappropriate (n = 75)P value
Cefepime141 (61.3)33 (44.0)0.009
Ceftazidime36 (15.7)3 (4.0)0.009
Piperacillin-tazobactam5 (2.2)3 (4.0)0.686
Imipenem31 (13.5)9 (12.0)0.742
Aminoglycosideb102 (44.3)30 (40.0)0.509
Ciprofloxacin32 (13.9)19 (25.3)0.021
Aztreonam1 (0.4)0 (0.0)>0.999
Other4 (1.7)2 (2.7)0.638
  • a Appropriate antimicrobial treatment was defined as in vitro susceptibility testing demonstrating a sensitive isolate of P. aeruginosa to the antimicrobial agent prescribed.

  • b Includes gentamicin, tobramycin, and amikacin.