TABLE 2.

Genotypes and phenotypes observed in our collection of N. gonorrhoeae strains isolated from sexually transmitted infections in New Caledoniaa

Type of porB alleleType of penA alleleNo. of strains with indicated type of ponA alleleTotal no. of strainsMIC for penicillin Gb
WTMutant
GA (WT)WT 54 14680.017*
Asp-345a311320.081†
Total8515100
DA (G101D)WT211220.016*
Asp-345a000
Total21122
GS (A102S)WT3030.133‡
Asp-345a467530.156‡
Total49756
porB1a WT1010200.011*
Asp-345a100100.070†
Total201030
Total17533208
  • a Two hundred eight strains were isolated between February 2005 and October 2007. Results for isolates with wild-type genotypes are underlined. None of the isolates contained the single −T deletion in the mtrR promoter, and only two of the isolates with low susceptibility had a G45S mutation in the mtrR gene. WT, wild type.

  • b Symbols indicate significantly different average MICs between genotypes (analysis of variance and Fischer's protected least significant difference test: 0.001 < P < 0.013).