TABLE 4.

Genes with expression changes of >8-fold between Mu3 and N315 parent and mutant strains (P < 0.05)

N315 ORFaGene nameProduct or putative functionFold change vsb:
Mu3N315
Mu3_mut1Mu3_mut2Mu3_mut3Mu3_mut4N315_mut1N315_mut2N315_mut3
SA0129LPXTG proteinNC−2.4−5.0−9.1NCNCNC
SA0214uhpTHexose phosphate transport proteinNCNCNCNC−16−34−21
SA0322mepRMarR-like transcriptional regulator103916683717178
SA0323mepAMATE family efflux pump9710010411110289106
SA0324mepBHypothetical protein8511511414210096106
SAS016Hypothetical proteinNCNCNCNC5.39.58.6
SA0889Hypothetical proteinNCNCNC2.310.75.811.3
SA1048pyrEOrotate phosphoribosyltransferaseNC−2.6−3.4−8.4NCNCNC
SA1203trpFAnthranilate isomeraseNCNCNCNC−6.3−10.5−7.1
SA1204trpBTryptophan synthaseNCNC2.02.1−6.4−8.2−7.9
SA1205trpATryptophan synthaseNCNCNC2.3−6.3−8.0−8.3
SA1898Hypothetical proteinNCNCNCNC169.019
SA2405betACholine dehydrogenase16.216.224.57.62.1NCNC
SA2406gbsAGlycine betaine aldehyde dehydrogenase6963104362.8NCNC
SAV0398ctet(M)Tetracycline resistance proteinNCNC4444NCNCNC
  • a Genes investigated in this report are highlighted in boldface type. ORF, open reading frame.

  • b NC, no change (<2-fold change in gene expression). Changes for genes with decreased expression are indicated with a minus sign.

  • c Mu50 open reading frame number.