TABLE 1.

MICs of quinolone and fluoroquinolones against E. coli TOP10 harboring recombinant plasmids pSmQnr1 to pSmQnr11a

StrainMIC (μg/ml)b
NALNORLVXCIPSPXGATMXF
E. coli TOP101.50.0320.0040.002<0.002<0.002<0.002
E. coli TOP10/pSmQnr13.00.0640.0230.0080.0040.0080.012
E. coli TOP10/pSmQnr22.00.0470.0120.004<0.002<0.002<0.002
E. coli TOP10/pSmQnr31.50.0320.0060.003<0.0020.0030.002
E. coli TOP10/pSmQnr41.50.0320.0060.002<0.0020.0020.002
E. coli TOP10/pSmQnr52.00.0320.0080.002<0.002<0.0020.003
E. coli TOP10/pSmQnr62.00.0640.0230.0160.1250.0640.047
E. coli TOP10/pSmQnr72.00.0470.0230.0080.0080.0230.008
E. coli TOP10/pSmQnr82.00.0470.0120.004<0.0020.0020.002
E. coli TOP10/pSmQnr91.50.0320.0080.003<0.0020.002<0.002
E. coli TOP10/pSmQnr102.00.0320.0230.0040.0020.0030.004
E. coli TOP10/pSmQnr112.00.0320.0120.006<0.0020.0030.002
  • a MICs of quinolone and fluoroquinolones against E. coli TOP10 and E. coli TOP10 harboring recombinant plasmids pSmQnr1, pSmQnr2, pSmQnr3, pSmQnr4, pSmQnr5, pSmQnr6, pSmQnr7, pSmQnr8, pSmQnr9, pSmQnr10, and pSmQnr11.

  • b NAL, nalidixic acid; NOR, norfloxacin; LVX, levofloxacin; CIP, ciprofloxacin; SPX, sparfloxacin; GAT, gatifloxacin; MXF, moxifloxacin.